As opposed to the VZ and all models previous which used Opel-sourced platforms adapted both mechanically and in size for the local market, the whole-new VE programme is the first Commodore to be developed exclusively by Holden in Australia. Despite its status as an all-new model, engines?comprising the 3.6-litre V6 and more powerful 6.0-litre V8?have been largely carried over from the VZ series. Innovative features to help minimise export redevelopment costs, such as a symmetrical centre console housing a flush-fitting hand brake lever, facilitate the conversion to left-hand drive. Internationally, the VE was badge engineered as the Chevrolet Lumina, Chevrolet Omega and Pontiac G8.

Holden implemented a staged roll-out of the VE variants, releasing the sedan first in July 2006. Prior to this, Holden stated they would manufacture two parallel generations of Commodores until the new station wagon and utility body styles were launched. Variants by Holden’s performance vehicle partner, Holden Special Vehicles (HSV), were released soon after the sedan’s debut alongside the long-wheelbase WM Statesman/Caprice models. The VE Ute did not enter production until 2007 when it was accompanied by the previewing of a Sportwagon concept. The Sportwagon itself was subsequently introduced in July 2008 with the standard Commodore wheelbase instead of the extended wheelbase of previous Commodore wagons.

Updates to the VE have come in the form of model year (MY) changes from early 2007 onwards. Typically subtle in nature, these recurring changes have involved alterations to colours and trim, increased standard equipment, and a reduction in fuel consumption. More noteworthy adjustments have come in the form of a smaller 3.0-litre V6 engine for entry-level versions and “Series II” styling revisions in late 2010.